Which of the Following Is Always Necessary for a Chemical

Which of the following is always necessary for a chemical reaction to occur between two reactants,A and B?

A)A and B must be present in the same physical state.
B)There must be equal amounts of A and B present.
C)A and B must collide with sufficient energy and the proper orientation.
D)The reaction must be carried out at room temperature.
E)The reaction must be carried out at a temperature higher than room temperature.

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