Which of the Following Is Not True of the Reaction
Which of the following is not true of the reaction catalyzed by glutamate dehydrogenase?
A)It is similar to transamination in that it involves the coenzyme pyridoxal phosphate (PLP).
B)NH4+ is produced.
C)The enzyme can use either NAD+ or NADP+ as a cofactor.
D)The enzyme is glutamate-specific,but the reaction is involved in oxidizing other amino acids.
E)-Ketoglutarate is produced from an amino acid.
Glutamate is metabolically converted to -ketoglutarate and NH4+ by a process described as:
The conversion of glutamate to an -ketoacid and NH4+:
A)does not require any cofactors.
B)is a reductive deamination.
C)is accompanied by ATP hydrolysis catalyzed by the same enzyme.
D)is catalyzed by glutamate dehydrogenase.
Urea synthesis in mammals takes place primarily in tissues of the: