Deck 30: the Chemical Senses
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Deck 30: the Chemical Senses
1
Increased C l- conductance in olfactory sensory neurons
A) Depolarizes the cells because C l- en ter s th e c ells
B) Depolarizes the cells because Cl- leav es th e ce lls
C) Hyperpolarizes the cells because C l- en ter s th e c ells
D) Hyperpolarizes the cells because C l- lea ve s th e c ells
E) Depolarizes the cells because Ca2+ en ter s th e c ells
A) Depolarizes the cells because C l- en ter s th e c ells
B) Depolarizes the cells because Cl- leav es th e ce lls
C) Hyperpolarizes the cells because C l- en ter s th e c ells
D) Hyperpolarizes the cells because C l- lea ve s th e c ells
E) Depolarizes the cells because Ca2+ en ter s th e c ells
B
2
The vagus nerve innervates
A) Circumvallate papillae at the back of the tongue
B) Foliate papillae in the anterior two thirds of the tongue
C) Fungiform papillae in the anterior two thirds of the tongue
D) Fungiform papillae at the back of the tongue
E) Taste buds in the pharynx
A) Circumvallate papillae at the back of the tongue
B) Foliate papillae in the anterior two thirds of the tongue
C) Fungiform papillae in the anterior two thirds of the tongue
D) Fungiform papillae at the back of the tongue
E) Taste buds in the pharynx
E
3
The salt-sensitive taste-receptor cells in humans would be blocked by
A) Am iloride
B) Eth ac ryn ic a cid
C) Ac id
D) Am monium
E) Cetylpyridinium chloride
A) Am iloride
B) Eth ac ryn ic a cid
C) Ac id
D) Am monium
E) Cetylpyridinium chloride
E
4
The sm ell of peppermint, menthol, chlorine and amm onia is unusual in that
A) Their sensory afferents are carried in the trigeminal nerve
B) The y use T1R 1 receptors
C) They use EnaC channels in their transduction mechanism
D) They are detected in the vomeronasal organ
E) They use a Gs mechanism for sensory transduction
A) Their sensory afferents are carried in the trigeminal nerve
B) The y use T1R 1 receptors
C) They use EnaC channels in their transduction mechanism
D) They are detected in the vomeronasal organ
E) They use a Gs mechanism for sensory transduction
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5
Humans do not discriminate well between the taste of NaCl and KCl because
A) The ion channel on the basolateral membrane is specific for Na+ ions
B) It is actually sensit ive to Cl-
C) The G-protein mechanism for salty taste b inds both Na+ and K+
D) The salty taste in humans is restricted to the circumvallate papillae
E) The ion channel in humans on the apical membrane lets either Na+ or K + into the cell.
A) The ion channel on the basolateral membrane is specific for Na+ ions
B) It is actually sensit ive to Cl-
C) The G-protein mechanism for salty taste b inds both Na+ and K+
D) The salty taste in humans is restricted to the circumvallate papillae
E) The ion channel in humans on the apical membrane lets either Na+ or K + into the cell.
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6
If you did not h ave a fun ctiona l gene for the T1 R3 rece ptor, you wou ld be u nab le to res pon d to
A) Sw eet ta stan ts
B) Bitter tas tants
C) Um am i tastan ts
D) Bo th sw eet a nd b itter tasta nts
E) Both sw eet and um am i tastants
A) Sw eet ta stan ts
B) Bitter tas tants
C) Um am i tastan ts
D) Bo th sw eet a nd b itter tasta nts
E) Both sw eet and um am i tastants
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7
Which of the following papillae DO NOT have taste buds?
A) Foliate papillae
B) Fungiform papillae
C) Circumvallate papillae
D) Filiform papillae
E) All of the above have taste buds
A) Foliate papillae
B) Fungiform papillae
C) Circumvallate papillae
D) Filiform papillae
E) All of the above have taste buds
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8
The T2R taste receptors
A) Allow response to salty substances
B) Are resp ons ibile for the swe et tas te
C) Resp ond to bitter tastants
D) Give us the umam i sense
E) Allow the s our m oda lity
A) Allow response to salty substances
B) Are resp ons ibile for the swe et tas te
C) Resp ond to bitter tastants
D) Give us the umam i sense
E) Allow the s our m oda lity
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9
Each olfactory sensory neuron
A) M ake s on ly on e od ora nt b ind ing pro tein
B) Makes only a few different types of odorant binding proteins
C) Makes about 1300 different types of odorant binding proteins
D) Do not derive sensory sensitivity from the odorant binding proteins
E) Us e od oran t bindin g pro teins to disc harg e us ed o dora nts
A) M ake s on ly on e od ora nt b ind ing pro tein
B) Makes only a few different types of odorant binding proteins
C) Makes about 1300 different types of odorant binding proteins
D) Do not derive sensory sensitivity from the odorant binding proteins
E) Us e od oran t bindin g pro teins to disc harg e us ed o dora nts
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10
The po stulate d fun ction o f the v om eron asa l orga n is to
A) Detect volatile organic solvents such as CHCl3 and CCl4
B) R es po nd to a m m on ia
C) Detect pheromones
D) Detect odorants such as peppermint or chlorine
E) Respond to volatile amines
A) Detect volatile organic solvents such as CHCl3 and CCl4
B) R es po nd to a m m on ia
C) Detect pheromones
D) Detect odorants such as peppermint or chlorine
E) Respond to volatile amines
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11
The "ho t" taste of jalap eno pep pers is due to
A) Eth ac ryn ic a cid
B) 6 9 tetrahydrocannabinol
C) Cetylpyridinium chloride
D) Ca ps aicin
E) Am iloride
A) Eth ac ryn ic a cid
B) 6 9 tetrahydrocannabinol
C) Cetylpyridinium chloride
D) Ca ps aicin
E) Am iloride
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12
Which of the following cell types are NOT found in the olfactory epithelium?
A) Su ste nta cu lar or s up po rtin g c ells
B) O lfa cto ry re ce pto r c ells
C) Ba sa l or s tem ce lls
D) Se cr etin g c ells
E) Pa rietal c ells
A) Su ste nta cu lar or s up po rtin g c ells
B) O lfa cto ry re ce pto r c ells
C) Ba sa l or s tem ce lls
D) Se cr etin g c ells
E) Pa rietal c ells
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13
Which of the following taste moda lities is NO T m ediated by a G-protein coupled rec eptor?
A) Sour
B) Sweet
C) Sa lt
D) Bitter
E) A and C are both correct
A) Sour
B) Sweet
C) Sa lt
D) Bitter
E) A and C are both correct
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14
Odorant binding to receptors on the olfactory sensory neurons does all of the following EXCEPT
A) Activates adenylyl cyclase
B) Increases Ca2+ entry
C) Opens a C l- channel
D) Hyp erp olar izes the cell
E) Ac tiva tes a G -p ro tein
A) Activates adenylyl cyclase
B) Increases Ca2+ entry
C) Opens a C l- channel
D) Hyp erp olar izes the cell
E) Ac tiva tes a G -p ro tein
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15
The facial nerve innervates
A) Circumvallate papillae at the back of the tongue
B) Foliate papillae in the anterior two thirds of the tongue
C) Fungiform papillae in the anterior two thirds of the tongue
D) Fungiform papillae at the back of the tongue
E) Taste buds in the pharynx
A) Circumvallate papillae at the back of the tongue
B) Foliate papillae in the anterior two thirds of the tongue
C) Fungiform papillae in the anterior two thirds of the tongue
D) Fungiform papillae at the back of the tongue
E) Taste buds in the pharynx
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16
The glossopharyngeal nerve innervates
A) Circumvallate papillae at the back of the tongue
B) Foliate papillae in the anterior two thirds of the tongue
C) Fungiform papillae in the anterior two thirds of the tongue
D) Fungiform papillae at the back of the tongue
E) Taste buds in the pharynx
A) Circumvallate papillae at the back of the tongue
B) Foliate papillae in the anterior two thirds of the tongue
C) Fungiform papillae in the anterior two thirds of the tongue
D) Fungiform papillae at the back of the tongue
E) Taste buds in the pharynx
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17
Which of the following taste moda lities is NO T m ediated by a G-protein coupled rec eptor?
A) Sa lt
B) Sweet
C) Bitter
D) Umami
E) All of the above are mediated by GPCR
A) Sa lt
B) Sweet
C) Bitter
D) Umami
E) All of the above are mediated by GPCR
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18
The olfactory epithelium is located in the
A) Nasal turbinates
B) Vom eronasal organ
C) Roo f of the nas al cavity
D) Taste buds
E) Trigem inal nerve
A) Nasal turbinates
B) Vom eronasal organ
C) Roo f of the nas al cavity
D) Taste buds
E) Trigem inal nerve
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