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Molecular Biology 5th Edition by Robert Weaver
Edition 5ISBN: 978-0073525327Molecular Biology 5th Edition by Robert Weaver
Edition 5ISBN: 978-0073525327 Exercise 1
An asparagine in a DNA-binding protein makes an important hydrogen bond with a cytosine in the DNA. Changing this glutamine to alanine prevents formation of this hydrogen bond and blocks the DNA-protein interaction. Changing the cytosine to thymine restores binding to the mutant protein. Present a plausible hypothesis to explain these findings.
Explanation
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Residue of asparagine incline to form hy...
Molecular Biology 5th Edition by Robert Weaver
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