Molecular Biology 5th Edition by Robert Weaver

Exercise 2

coli promoter recognized by the RNA polymerase holoenzyme containing 70 has a 210 box with the following sequence in the nontemplate strand: 5-CATAGT-3. (a) Would a CT mutation in the first position likely be an up or a down mutation (b) Would a TA mutation in the last position likely be an up or down mutation Explain your answers.