Urinalysis and Body Fluids 6th Edition by Majorie DiLorenzo, Susan Strasinger

Exercise 10

A rapid immunologic test for FLM that does not require performance of thin-layer chromatography is:

A. AFP levels

B. Amniotic acetylcholinesterase

C. Aminostat-FLM

D. Bilirubin scan

Step 1 of 2

Phosphatidyl glycerol:

Phosphatidyl Glycerol (PG) is another lung-surface lipid that is essential for adequate lung maturity. It is detected in amniotic fluid after the gestation period of 35 weeks.

• Lecithin production is parallel to the production of PG, but during maternal diabetes the production of PG is delayed

• Accurate measurement of FLM (fetal lung maturity) can be provided by thin-layer chromatography, which includes Lecithin, PG, and Sphingomyelin

• But, development of an immunologic agglutination test such as Aminostat-FLM for PG provides more easy and rapid method to assess fetal maturity

• The assessment using Aminostat-FLM does not require a laboratory equipped to perform thin-layer chromatography.

Therefore, the immunologic test which does not require thin layer chromatography to assess FLM is “Aminostat-FLM”. Hence, the correct answer is option.