Urinalysis and Body Fluids 6th Edition by Majorie DiLorenzo, Susan Strasinger

Exercise 44

Detection of the CA 125 tumor marker in peritoneal fluid indicates:

A. Colon cancer

B. Ovarian cancer

C. Gastric malignancy

D. Prostate cancer

Step 1 of 2

“CA 125” in peritoneal fluid:

• Ascitic exudates of peritoneal fluid is examined for malignancy

• Malignant cells of prostatic, colonic, and ovarian origin are often seen in ascitic fluid

• The tumor marker CEA (Carcinoembryogenic antigen) and CA (Cancer Antigen or Carbohydrate Antigen or Carcinoma Antigen) 125 is used to identify source of tumors that forms ascitic exudates

• CA 125 antigen presence with negative CEA suggests that the cells are from ovaries, endometrium, and fallopian tubes

• Discovery of CA 125 tumor marker in peritoneal fluid indicates ovarian cancer

Therefore, identification of “CA 125” tumor marker in peritoneal fluid denotes “ovarian cancer”. Hence, the correct answer is option.