Urinalysis and Body Fluids 6th Edition by Majorie DiLorenzo, Susan Strasinger

Exercise 42

The presence of WBCs and WBC casts with no bacteria is indicative of:

A. Chronic pyelonephritis

B. Acute tubular necrosis

C. Acute interstitial nephritis

D. Both B and C

Step 1 of 2

Acute interstitial nephritis:

It is an interstitial disorder indicated by inflammation in renal tubules.

• Allergic reaction to medications in the renal interstitium occurs because medication binds to interstitial protein.

• Symptoms include fever, skin rash, oliguria, decreased renal concentrating ability, edema and decrease in glomerular filtration rate.

• Symptoms show after two weeks of medications.

• Urinalysis results show WBC (White Blood Cell) casts without bacteria, hematuria, moderate proteinuria, WBCs.

Therefore, WBC and WBC casts without bacteria is an indication of “acute interstitial nephritis”. Hence, the correct answer is option.