Urinalysis and Body Fluids 6th Edition by Majorie DiLorenzo, Susan Strasinger

Exercise 32

An inherited disorder producing a generalized defect in tubular reabsorption is:

A. Alport syndrome

B. Acute interstitial nephritis

C. Fanconi syndrome

D. Renal glycosuria

Step 1 of 2

Fanconi syndrome:

It is a metabolic and hereditary tubular disorder.

• This syndrome indicates failure of tubular reabsorption which occurs in proximal convoluted tubule.

Reabsorption is affected by

• Dysfunction in transport of filtered elements in tubular membranes.

• Disturbance in cellular energy which is required for transport.

• Change in permeability of tubular membrane

Therefore, generalized defect in tubular reabsorption is seen in inherited disorder “Fanconi syndrome”. Hence, the correct answer is option .