Urinalysis and Body Fluids 6th Edition by Majorie DiLorenzo, Susan Strasinger

Exercise 12

Antiglomerular basement membrane antibody is seen with:

A. Wegener granulomatosis

B. IgA nephropathy

C. Goodpasture syndrome

D. Diabetic nephropathy

Step 1 of 2

Good pasture syndrome:

• Progressive glomerular nephritis combined with autoimmune disorder is termed as good pasture syndrome.

• An auto antibody which is cytotoxic will appear against alveolar basement membrane and glomerular after respiratory viral infections

• This is followed by activation of compliment producing capillary destruction which is called as antiglomerular basement membrane antibody.

• It is detected in patient’s serum.

Therefore, “good pasture syndrome” is seen with antiglomerular basement membrane antibody. Hence, the correct answer is option .