Urinalysis and Body Fluids 6th Edition by Majorie DiLorenzo, Susan Strasinger

Exercise 9

Occasional episodes of macroscopic hematuria over periods of 20 or more years are seen with:

A. Crescentic glomerulonephritis

B. IgA nephropathy

C. Nephrotic syndrome

D. Wegener granulomatosis

Step 1 of 2

Immunoglobulin A nephropathy:

• It is the common cause of glomerulonephritis and also called as berger disease.

• Immune complexes IgA deposits in glomerular membrane and the patient’s serum have IgA in increased level.

• Macroscopic hematuria is caused by strenuous sports or infections.

• Occasional macroscopic hematuria for 20 years is seen IgA nephropathy.

• Immunoglobulin A nephropathy progresses to chronic glomerulonephritis, finally to terminal stage of renal disease.

Therefore, macroscopic hematuria over 20 years is seen with “IgA nephropathy”. Hence, the correct answer is option .