Urinalysis and Body Fluids 6th Edition by Majorie DiLorenzo, Susan Strasinger

Exercise 3

Most glomerular disorders are caused by:

A. Sudden drops in blood pressure

B. Immunologic disorders

C. Exposure to toxic substances

D. Bacterial infections

Step 1 of 2

Glomerulus:

• Glomerulus is the part of nephron which is a network of capillaries.

• Nephron is the functional unit of kidney.

Glomerular disorders:

• Most glomerulus disorders are caused due to immunologic disorders in the body.

• Immune complexes are produced by immunologic reaction and increase of Immunoglobulin A (IgA) circulates in blood stream and deposits on glomerular membrane.

• Components of immune system attracts to glomerular membrane then produce changes and damages to membrane.

• Damage can be cellular proliferation and infiltration which leads to glomerular basement membrane thickening.

• Capillaries and basement membrane are then damaged.

Therefore, “immunologic disorders” causes most glomerular disorders. Hence, the correct answer is option .