Deck 39: Treatment of Fungal Infections

Question 1

_____ is the only antifungal belonging to the thiocarbamate class.

A)Tolnaftate
B)Thionate
C)Thymolate
D)Tolecinate

Answer 1

A
Tolnaftate is the only antifungal belonging to the thiocarbamate class.

Question 2

Which of the following is not a mechanism of action of antifungal agents?

A)destroying the fungus's cell membrane
B)interfering with the synthesis of nucleic acids needed for replication
C)inhibiting the synthesis of the fungal cell wall
D)interrupting protein formation

Answer 2

D
There are three primary mechanisms of action for antifungal agents.Most antifungal agents act by destroying the fungus's cell membrane.The cell membrane of fungi differs from the cell membrane of human cells so destruction of the fungi does not destroy the human cell.A second mechanism is interference with the synthesis of nucleic acids needed for replication.A third mechanism is to inhibit the synthesis of the fungal cell wall.

Question 3

All of the following drugs are derived from the fungi-like bacteria Streptomyces except _____.

A)nystatin
B)miconazole
C)natamycin
D)amphotericin B

Answer 3

B
Nystatin,natamycin,and amphotericin B are all derived from the fungi-like bacteria Streptomyces.

Question 4

Pneumocystis carinii is a fungus that can cause pneumonia in individuals who have a decreased immune system response.

Question 5

By which route of administration is griseofulvin administered to treat onychomycosis?

A)topical
B)oral
C)subcutaneous into the nail bed
D)a and b

Question 6

A Candida infection in the oral cavity is called thrush and is most common in what age group?

A)toddlers
B)infants
C)school-age children
D)all of the above

Question 7

Anidulafungin,caspofungin,and micafungin belong to a class of antifungal agents called echinocandins.They are effective for treating infections caused by which fungi?

A)Candida
B)Aspergillus
C)tinea
D)a and b

Question 8

Which of the following fungal infections cannot be cured using OTC drugs?

A)vulvovaginal candidiasis
B)thrush
C)jock itch
D)athlete's foot

Question 9

To identify the fungus Candida,a potassium _____ stain is applied to a sample of cells from the infected area.

A)chloride
B)iodide
C)hydroxide
D)sulfide

Question 10

Which of the following is true about dermatophytes?

A)They live on the top layer of the skin,hair,and nails.
B)They are usually found in the mouth.
C)They thrive in the vaginal mucosa.
D)All of the above are true.

Question 11

No fungus is beneficial because they all cause disease.

Question 12

Women taking a broad-spectrum antibiotic for a bacterial infection may develop _____ as a result.

A)a yeast infection
B)a rash
C)onychomycosis
D)thrush

Question 13

Which of the following is not true about ringworm?

A)It is contagious.
B)It can spread between humans and animals.
C)It is not spread from person to person.
D)It is caused by a fungus,not a worm.

Question 14

The mechanism of action of imidazoles and triazoles is that they interfere with _____.

A)egestrol,part of the fungal cell membrane
B)ergosterol,an essential component needed for synthesis of the fungal cell membrane
C)the blocking of an enzyme needed for the synthesis of ergosterol
D)the alkaloid necessary for cell membrane synthesis

Question 15

Candida is called yeast and is a fungus.

Question 16

Candida is normally present in what parts of the body but only causes infection when conditions are favorable to the overgrowth of yeast?

A)GI tract
B)between the toes
C)vagina
D)a and c

Question 17

Which of the following "azoles" require a prescription?

A)terconazole
B)butoconazole
C)ketoconazole
D)miconazole

Question 18

Ringworm can spread between human and animals.

Question 19

Athlete's foot (tinea pedis)is a common fungal infection that affects only athletes.