Deck 10: Pharmacology

Question 1

A subacute toxic effect occurs when the adverse drug effect occurs

A)after 5 minutes of exposure.
B)after 24 hours of exposure.
C)after repeated exposure for days.
D)over months to years of exposure.

Answer 1

C

Question 2

Which of the following is a phase I reaction in biotransformation?

A)Oxidation
B)Conjugation
C)Acetylation
D)Glucuronidation

Answer 2

A

Question 3

Drug administration,absorption,distribution,and clearance are collectively called __________.

Answer 3

pharmacokinetics

Question 4

The generic name of a drug refers to its __________ name.

A)trade
B)proprietary
C)chemical
D)nonproprietary

Question 5

The time response measures all of the following except

A)ED50
B)Peak effect time
C)Onset of response
D)Threshold level

Question 6

The decrease in blood clotting by heparin occurs at which general site of action?

A)Cellular
B)Extracellular
C)Neuromuscular
D)Intracellular

Question 7

The study of the body's response to poisons and their harmful effect is referred to as __________.

Question 8

The body's metabolism of drugs is called __________.

Question 9

When drug receptors are maximally activated it is referred to as the

A)threshold level.
B)peak effect.
C)cessation effect.
D)latency time.

Question 10

The discipline addressing issues associated with the choice and application of drugs to be used for disease prevention,treatment,and/or diagnosis is

A)pharmacotherapeutics.
B)toxicology.
C)pharmacokinetics.
D)pharmacy.

Question 11

The term used to indicate the extent to which a drug reaches its site of action is

A)bioactivity.
B)bioavailability.
C)bioremediation.
D)biostasis.

Question 12

The federal agency that approves the use of a specific drug is the __________.

Question 13

ED₅₀ is a measure of the __________ response.

Question 14

Drugs needed for diseases with fewer than 200,000 patients,and that fail to receive attention for development because of cost and need,are called

A)secondary drugs.
B)minor drugs.
C)orphan drugs.
D)specialty drugs.

Question 15

All of the following are ways the kidney are used for urine formation and drug clearance except

A)Filtration
B)Tubular secretion
C)Tubular filtration
D)Tubular reabsorption

Question 16

Drugs are excreted from the body primarily via the

A)lungs.
B)kidneys.
C)small intestines.
D)spleen.

Question 17

The branch of pharmacology that addresses drug amounts at various sites in the body after drug administration is called

A)pharmacodynamics.
B)pharmacokinetics.
C)pharmacotherapeutics.
D)pharmacy.

Question 18

The most rapid rate of drug absorption is achieved by __________ administration.

A)on the skin
B)intravenous
C)intramuscular
D)sublingual

Question 19

The specific antidote to botulinum toxin is

A)sodium bicarbonate.
B)antitoxin.
C)pralidoxime.
D)naloxone.

Question 20

A mercury-containing compound used as a preservative in vaccines is

A)analgesic.
B)EDTA.
C)codeine.
D)thimerosal.

Question 21

A __________ name is a nonproprietary single name usually related to the drug's relationship to a therapeutic class.

Question 22

Match the description below with the correct item from this list.
a.Morphine
b.Administered into the subarachnoid space
c.Diazepam
d.Administered into muscles
e.Aspirin
f.Administered sublingually
g.L-Dopa
h.LSD
Schedule II controlled substance

Question 23

Match the description below with the correct item from this list.
a.Morphine
b.Administered into the subarachnoid space
c.Diazepam
d.Administered into muscles
e.Aspirin
f.Administered sublingually
g.L-Dopa
h.LSD
Schedule I controlled substance

Question 24

The __________ is the ratio between a drug dose causing undesirable effects and the dose that causes the desired effects.

Question 25

Match the description below with the correct item from this list.
a.Morphine
b.Administered into the subarachnoid space
c.Diazepam
d.Administered into muscles
e.Aspirin
f.Administered sublingually
g.L-Dopa
h.LSD
Schedule IV controlled substance

Question 26

Match the description below with the correct item from this list.
a.Morphine
b.Administered into the subarachnoid space
c.Diazepam
d.Administered into muscles
e.Aspirin
f.Administered sublingually
g.L-Dopa
h.LSD
Prodrug

Question 27

Drugs and substances with a high probability for abuse with no therapeutic use and a lack of safety controls are classified as Schedule __________.

Question 28

Match the description below with the correct item from this list.
a.Morphine
b.Administered into the subarachnoid space
c.Diazepam
d.Administered into muscles
e.Aspirin
f.Administered sublingually
g.L-Dopa
h.LSD
Intrathecally

Question 29

The three general sites of drug action are __________,__________,and __________.

Question 30

The __________ effect is the combined action of intestinal and hepatic drug-metabolizing enzymes that affects a drug's bioavailability.