Deck 6: System-Based and Situational Viral Infections

Question 1

An 8-year-old boy is brought to your office by his mother. He has had a slight fever and a sore throat for the past 2 days. He has eight ulcerative lesions in his mouth, three vesicular lesions on his left hand, and five similar lesions on his right foot. The most probable cause of his disease is

A) Coxsackie A virus
B) Human herpes virus 6
C) HSV
D) HPV

Answer 1

Coxsackie A virus

Question 2

A 16-year-old boy presents at your office with a sore throat, fever, and enlarged lymph nodes. His tonsils are enlarged, the pharynx is inflamed, and splenomegaly is observed. He complains of severe fatigue. Confirmation of the causative agent is best done by observing

A) A positive Tzanck smear
B) IgM heterophile antibodies
C) Koilocytotic cells
D) RT-PCR for enterovirus

Answer 2

IgM heterophile antibodies

Question 3

The most common cause of congenital infections is

A) CMV
B) HSV
C) Parvovirus
D) Rubella virus

Answer 3

CMV

Question 4

A 23-year-old medical student on the Caribbean island of Dominica presents at the Student Health Clinic complaining of an increasingly severe headache and back and bone pain. Yesterday she was nauseated and vomited several times during the night. She has a 39.5°C/103°F fever, which appeared suddenly, and a generalized rash that blanches under pressure. She had been hiking in the rainforest 1 week earlier and was particularly bothered by mosquitoes at that time. The most likely infectious agent causing her symptoms is

A) Dengue virus
B) LCM virus
C) West Nile virus
D) Yellow fever virus

Question 5

A 4-year-old girl is brought to your rural clinic office by her mother who states the child has a runny nose, barking cough, and a sore throat. Your examination indicates respiration is labored. None of her three siblings is sick. The most probable viral cause of her symptoms is

A) Adenovirus
B) Influenza virus
C) Parainfluenza virus
D) RSV

Question 6

The individual most likely to develop chronic liver disease is a

A) 1-month-old infant infected with HBV
B) 22-year-old coinfected with HBV and HDV
C) 26-year-old alcoholic intravenous drug abuser infected with HBV
D) 30-year-old infected with yellow fever virus

Question 7

A 64-year-old man living on a farm in southern Minnesota is brought on July 15 to the emergency room by his brother. The brother said the man had a 2-day history of fever, headache, and some vomiting, but today he appeared confused. He is confused by some of the simple questions you ask him. His spinal tap is clear with 75% PMNs and a head CT is normal. The most likely cause of his symptoms is

A) California encephalitis virus
B) Enterovirus
C) HSV
D) West Nile virus

Question 8

A mother brings her 18-month-old son to your office. She was called by her day care center who reported he had vomited twice during the morning and had diarrhea as well. She noted he had a slight fever the past 2 days and had not been very hungry. The most likely cause of his illness is

A) Adenovirus
B) Astrovirus
C) Norovirus
D) Rotavirus

Question 9

A vaccine is available for protection against the disease observed in review question 8. The immunizing agent(s) for this vaccine is a(n)

A) Attenuated virus
B) Formalin-inactivated virus
C) Preparation of reassortment viruses
D) Viral attachment protein preparation

Question 10

Donors for liver transplants must be monitored and determined to be serologically negative for previous

A) CMV infections
B) EBV infections
C) HBV infections
D) HEV infections

Question 11

On September 17, a 22-year-old male college student appears at the Student Health Clinic complaining of moderate headache, nausea, and vomiting. His temperature is 38.5°C/101°F and his physical examination shows stiffness in the neck. What is the most likely viral cause of the symptoms?

A) CMV
B) Enterovirus
C) EBV
D) HSV type 1

Question 12

Knowing the genotype of the causative virus is important for determining the treatment of chronic

A) CMV infections
B) HCV infections
C) IC virus infections
D) VZV infections