Deck 18: Antifungal Agents

Question 1

A fungal infection is termed a:

A) local infection
B) phagocytosis
C) mycosis
D) filamentous

Answer 1

mycosis

Question 2

A common candidiasis infection of the mouth is known as:

A) thrush
B) aspergillosis
C) thrombophlebitis
D) gossypol

Answer 2

thrush

Question 3

The term fungicidal is defined as:

A) having a killing action on protozoans
B) increasing fungal growth
C) slowing fungal growth without destroying the fungi
D) having a killing action on fungi

Answer 3

having a killing action on fungi

Question 4

The drug with the widest spectrum of antifungal activity is:

A) griseofulvin
B) amphotericin B
C) flucytosine
D) ketoconazole

Question 5

Most antifungal drugs act by interfering with the synthesis of:

A) fluorouracil
B) gossypol
C) moniliasis
D) ergosterol

Question 6

The most serious adverse effect of amphotericin B is:

A) fever
B) renal damage
C) thrombophlebitis
D) loss of hearing

Question 7

The drug of choice to treat chromomycosis is:

A) ketoconazole
B) amphotericin B
C) fluorouracil
D) flucytosine

Question 8

Severe cutaneous dermatophyte infections that resist griseofulvin therapy should be treated with:

A) flucytosine
B) chloroquine
C) ketoconazole
D) amphotericin B

Question 9

Griseofulvin is fungistatic and NOT fungicidal, and must be used systemically:

A) for a long period of time
B) to kill all remaining fungi
C) in patients with porphyria
D) to increase contraceptive efficacy

Question 10

Fungal superinfections usually occur in the anal, genital, and:

A) skin areas
B) eye areas
C) oral areas
D) ear areas

Question 11

A fungus is a one-celled plant that lacks:

A) virulence
B) spores
C) color and chlorophyll
D) pathogenicity

Question 12

The trade name for nystatin is:

A) Flucytosine
B) Pentamidine
C) Lovastatin
D) Mycostatin

Question 13

Candidiasis may occur because of an overgrowth of:

A) yeast-like fungi
B) mold-like fungi
C) tissue
D) a certain type of worm

Question 14

Which of the following is derived from fungi?

A) vaccines
B) immunoglobulins
C) antitoxins
D) antiviral agents

Question 15

Which of the following is NOT a risk factor for candidal infections?

A) diabetes
B) hypertension
C) pregnancy
D) administration of corticosteroids

Question 16

The trade name of fluconazole is:

A) Diflucan
B) Grifulvin V
C) Amphocin
D) Mycamine

Question 17

The most serious toxic effect of amphotericin B is:

A) liver damage
B) deafness
C) retinopathy
D) kidney damage

Question 18

Griseofulvin is contraindicated in patients with:

A) cataracts
B) porphyria
C) gastritis
D) pancreatitis

Question 19

Onychomycosis is also known as:

A) tinea unguium
B) tinea corporis
C) tinea barbae
D) tinea pedis

Question 20

Micafungin should NOT be given to patients who have which of the following?

A) fever or chills
B) liver or kidney disease
C) fungal infections
D) heart failure

Question 21

Terbinafine (Lamisil ) is used for the treatment of:

A) histoplasmosis
B) candidiasis
C) blastomycosis
D) onychomycosis

Question 22

The trade name of sulconazole is:

A) Oxistat
B) Monistat
C) Exelderm
D) Tinactin

Question 23

The trade name of tioconazole is:

A) Monistat
B) Tinactin
C) Oxistat
D) Naftin

Question 24

Cryptococcal meningitis can be treated by intravenous injection of the antifungal agent known as:

A) griseofulvin
B) fluconazole
C) voriconazole
D) itraconazole

Question 25

Which of the following systemic antifungal agents can be administered intravenously?

A) fluconazole (Diflucan )
B) ketoconazole (Nizoral )
C) griseofulvin (Grifulvin V )
D) caspofungin (Cancidas )

Question 26

The trade name of posaconazole is:

A) Noxafil
B) Lamisil
C) Vfend
D) Nystex

Question 27

Which of the antifungal agents may cause angioedema, taste sensation changes, and hepatitis?

A) caspofungin
B) fluconazole
C) amphotericin B
D) flucytosine

Question 28

The trade name of voriconazole is:

A) Nizoral
B) Grifulvin V
C) Vfend
D) Lamisil

Question 29

Onychomycosis is a chronic fungal disease of the:

A) skin
B) nails
C) hair
D) sweat glands

Question 30

The trade name of butenafine is:

A) Naftin
B) Mycostatin
C) Lotrimin
D) Mentax