Genetics: Analysis and Principles 4th Edition by Robert Brooker

تمرين 6

Cystic fibrosis (CF) is a recessive autosomal trait. In certain Caucasian populations, the number of people born with this disorder is about 1 in 2500. Assuming Hardy-Weinberg equilibrium for this trait,
A. What are the frequencies for the normal and CF alleles
B. What are the genotype frequencies of homozygous normal, heterozygous, and homozygous affected individuals
C. Assuming random mating, what is the probability that two phenotypically unaffected heterozygous carriers will choose each other as mates