In a CNG knockout mouse:
A) Kirrel2 levels should be high in all/most ORNs.
B) EphA levels should be high in all/most ORNs.
C) ORN axons of at least some classes should fail to converge on a single glomerulus.
D) All of the above
E) None of the above

Question

Quizplus · Accepted Answer

When CNG activity is low (or absent), Kirrel2 and EphAexpression levels should be low, while Kirrel3 and ephrin-Alevels should be high. This lack of an expression gradient will disrupt refinement of glomerular targeting.

In a CNG Knockout Mouse