In many cells, the adhesion to the extracellular matrix through integrins causes the activation of kinases in the cytoplasm. This suggests that:
A)integrins promote the activation of signal-transduction pathways.
B)integrins are kinases.
C)extracellular matrix proteins are receptors and integrins are ligands.

Question

Quizplus · Accepted Answer

The fact that integrin adhesion to the extracellular matrix causes the activation of kinases suggests that integrins promote the activation of signal-transduction pathways. This means that integrins transmit signals from the outside of the cell to the cytoplasm, which involves the activation of intracellular signaling pathways.

In Many Cells, the Adhesion to the Extracellular Matrix Through