Which one of the following statements about integrins is CORRECT?
A)Integrins indirectly connect microfilaments with the extracellular matrix.
B)There is a single type of integrin, capable of binding to multiple types of extracellular matrix proteins.
C)Integrins are the primary cell adhesion molecule in a desmosome.
D)Adjacent integrins create channels referred to as gap junctions.

Question

Quizplus · Accepted Answer

Integrins indirectly connect microfilaments with the extracellular matrix by binding to cytoskeletal proteins such as talin on the inside of the cell and to extracellular matrix proteins such as fibronectin and collagen on the outside of the cell. Option B is incorrect because there are many types of integrins that bind to specific extracellular matrix proteins. Option C is incorrect because desmosomes primarily utilize cadherins as cell adhesion molecules. Option D is incorrect because gap junctions are formed by connexins, not integrins.

Which One of the Following Statements About Integrins Is CORRECT