When Considering Complex Traits in Health and Disease, Which of the Following

When considering complex traits in health and disease, which of the following statements is NOT correct?

A) Diabetes, high blood pressure, asthma, epilepsy, schizophrenia, and clinical depression are all complex traits.
B) Cystic fibrosis, sickle-cell anemia, and phenylketonuria are simple Mendelian disorders.
C) The majority of birth anomalies result only from genetic risk factors.
D) Many genes that contribute to complex traits are clustered on the same chromosome.
E) Many genes that contribute to complex traits arose through the process of duplication of a single gene followed by divergence over time, generating a family of genes near one another with related functions.