If a mutation rendered the signal recognition particle nonfunctional, what would be the MOST obvious effect on the cell?
A)Translation would not be completed for most proteins.
B)All proteins normally secreted by the cell would remain partially formed and attached to the endoplasmic reticulum.
C)Proteins destined for the nucleus would remain in the cytosol.
D)No proteins would arrive at their proper destinations within the cell.
E)All proteins normally secreted by the cell would remain in the cytosol.

Question

Quizplus · Accepted Answer

The signal recognition particle (SRP) is crucial for directing ribosomes that synthesize certain proteins to the endoplasmic reticulum (ER) for further processing and eventual secretion out of the cell. If the SRP is nonfunctional, proteins that are normally secreted would not be directed to the ER and would instead accumulate in the cytosol.

If a Mutation Rendered the Signal Recognition Particle Nonfunctional, What