Which residues are MOST likely to be enriched in an intrinsically disordered protein that is soluble in water?
A) Y, K, W
B) E, C, F
C) V, I, L
D) R, K, A
E) H, F, W

Question

Quizplus · Accepted Answer

Intrinsically disordered proteins (IDPs) that are soluble in water tend to have a high proportion of charged and polar amino acids, which help them remain soluble and avoid folding into a stable 3D structure. Arginine (R), lysine (K), and alanine (A) are examples of such amino acids, with R and K being positively charged and A being small and polar, making them conducive to disorder and solubility in aqueous environments.

Which Residues Are MOST Likely to Be Enriched in an Intrinsically