In a multiple regression with five predictors in a sample of 56 U.S.cities,we would use F5,50 in a test of overall significance.

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This is true because F5,50 represents the F-statistic with 5 predictors and 50 degrees of freedom for error in a multiple regression analysis. It is used to test the overall significance of the model, which tests whether the predictors as a group significantly predict the outcome variable.

In a Multiple Regression with Five Predictors in a Sample