"The native structure of h[a]emoglobin (Hb) comprises of two α and two β subunits, each of which carries a h[a]em group. There appear to be no previous studies that report the in-vitro folding and assembly of Hb from highly unfolded α and β globin in a 'one-pot' reaction. One difficulty that has to be overcome for studies of this kind is the tendency of Hb to aggregate during refolding. This work demonstrates that denaturation of Hb in 40% acetonitrile at pH 10.0 is reversible." (J Am Soc Mass Spectrum 2007, 18, 8-16)
-Haemoglobin is ________.
A) a tertiary protein with two polypeptides
B) a quaternary protein with two polypeptides
C) a tertiary protein with four polypeptides
D) a quaternary protein with four polypeptides

Question

Quizplus · Accepted Answer

The native structure of haemoglobin comprises of two α and two β subunits, indicating that it is a quaternary protein with four polypeptides.

"The Native Structure of H[a]emoglobin (Hb) Comprises of Two α