A researcher found a method he could use to manipulate and quantify phosphorylation and methylation in embryonic cells in culture. In one set of experiments, he succeeded in increasing acetylation of histone tails in the chromatin of the cells. Which of the following results would he most likely see in these cells?
A) increased chromatin condensation
B) decreased chromatin condensation
C) decreased binding of transcription factors
D) inactivation of the selected genes

Question

Quizplus · Accepted Answer

Acetylation of histone tails is associated with an open chromatin structure that allows for transcription factor binding and gene expression. Therefore, it is likely that increased acetylation would lead to decreased chromatin condensation and increased expression of the selected genes.

A Researcher Found a Method He Could Use to Manipulate