Figure 7.1
-Starting with one molecule of isocitrate and ending with fumarate, how many ATP molecules can be made through substrate-level phosphorylation (see Figure 7.1)?
A) 1
B) 2
C) 11
D) 12
E) 24

Question

Figure 7.1
-Starting with one molecule of isocitrate and ending with fumarate, how many ATP molecules can be made through substrate-level phosphorylation (see Figure 7.1)?
A) 1 
B) 2 
C) 11 
D) 12 
E) 24

Quizplus · Accepted Answer

Substrate-level phosphorylation in the citric acid cycle occurs when succinyl-CoA is converted to succinate, producing one GTP (or ATP) per cycle. Starting with isocitrate and ending with fumarate involves one cycle, thus producing one ATP.

Figure 7.1 -Starting with One Molecule of Isocitrate and Ending with Fumarate