Match each of the following descriptions in questions with the appropriate disease (A-G).
-Defect in lymphocyte activation due to mutations in the gene encoding the SAP adapter protein required for inhibition of signaling by the SLAM molecule.Lack of SAP results in uncontrolled B cell proliferation,hypogammaglobulinemia,and B cell lymphoma in the setting of Epstein-Barr virus (EBV)infection.
A)X-linked agammaglobulinemia
B)X-linked hyper-IgM syndrome
C)X-linked lymphoproliferative syndrome
D)Class II MHC deficiency
E)Chronic granulomatous disease (CGD)
F)Leukocyte adhesion deficiency-1 (LAD-1)
G)Leukocyte adhesion deficiency-2 (LAD-2)

Question

Quizplus · Accepted Answer

X-linked lymphoproliferative syndrome is characterized by a severe CD8+ T cell response to Epstein-Barr virus (EBV),the virus that causes infectious mononucleosis.In a way,this is an example of a lethal exaggerated response to an infection,rather than a true immunodeficiency.

Match Each of the Following Descriptions in Questions with the Appropriate