The correct sequence for the hormone-activated enzymatic cascade that leads to activation of glycogen phosphorylase is:
A.Phosphorylation to activate phosphorylase kinase
B.Activation of G-protein
C.Activation of adenylyl cyclase to produce cAMP
D.Phosphorylation of glycogen phosphorylase
E.cAMP activation of protein kinase A (PKA)
A) A, B, C, D, E
B) B, C, E, A, D
C) C, B, A, D, E
D) B, D, E, A, C
E) E, A, D, C, B

Question

Quizplus · Accepted Answer

The correct sequence for the hormone-activated enzymatic cascade that leads to activation of glycogen phosphorylase is the following:

1. Activation of G-protein
2. Activation of adenylyl cyclase to produce cAMP
3. cAMP activation of protein kinase A (PKA)
4. Phosphorylation to activate phosphorylase kinase
5. Phosphorylation of glycogen phosphorylase

Therefore, the correct sequence is B) B, C, E, A, D.

The Correct Sequence for the Hormone-Activated Enzymatic Cascade That Leads