A mutation occurs such that a spliceosome cannot remove one of the introns in a gene. What effect will this have on that gene?
A) It will have no effect; the gene will be transcribed and translated into protein.
B) Transcription will terminate early and the protein will not be made.
C) Transcription will proceed, but translation will stop at the site where the intron remains.
D) Translation will continue, but a nonfunctional protein will be made.
E) Translation will continue and will skip the intron sequence.

Question

Quizplus · Accepted Answer

If a spliceosome cannot remove one of the introns in a gene, the pre-mRNA will contain the intron sequence. This will cause a frameshift mutation during translation and the resulting mRNA will code for a nonfunctional protein. Therefore, translation will continue, but the protein will be nonfunctional.

A Mutation Occurs Such That a Spliceosome Cannot Remove One