How does cAMP modulate protein kinase A activity?
A) It binds to a site on the C subunit to activate it
B) It binds to the R subunit leading to a conformation change
C) It causes association of the R and C subunits
D) It causes phosphorylation of the C subunit to release the R subunit
E) It competes with the R subunit for the active site of the C subunit

Question

Quizplus · Accepted Answer

Cyclic AMP (cAMP) binds to the regulatory (R) subunit of protein kinase A (PKA), leading to a conformational change that releases the catalytic (C) subunits, thereby activating the enzyme.

How Does CAMP Modulate Protein Kinase a Activity