The complement cascade:
A) Is triggered by the binding of Clq to multiple Fc units of antibody-antigen complexes.
B) Consists of a series of zymogens that are sequentially activated by proteolytic cleavage.
C) Ultimately results in the production of large pores in the plasma membrane of the target cell mediated by C9.
D) All of the above.
E) None of the above.

Question

Quizplus · Accepted Answer

The complement cascade is triggered by the binding of Clq to multiple Fc units of antibody-antigen complexes. It consists of a series of zymogens that are sequentially activated by proteolytic cleavage. Ultimately, it results in the production of large pores in the plasma membrane of the target cell mediated by C9. Therefore, all of the above statements are true.

The Complement Cascade