Which of the following would be required for the efficient expression of human low density lipoprotein (LDL) in a bacterial host?
A) a cDNA construct encoding LDL, under the control of a bacterial promoter
B) the human gene encoding LDL, under the control of a bacterial promoter
C) a cDNA construct encoding LDL, under the control of the LDL promoter
D) the human gene encoding LDL, under the control of the LDL promoter

Question

Quizplus · Accepted Answer

A cDNA construct encoding LDL, under the control of a bacterial promoter, is required for efficient expression in a bacterial host because cDNA lacks introns, which bacteria cannot process, and the bacterial promoter ensures the gene is recognized and transcribed efficiently in the bacterial system.

Which of the Following Would Be Required for the Efficient