In a simple protein molecule in aqueous solution, the charged groups
A) are almost all on the surface.
B) are mostly engaged in intramolecular electrostatic bonds.
C) are completely accounted for by the side chains of the basic and acidic amino acids.
D) have pK's below the solution pH.
E) all of the above

Question

Quizplus · Accepted Answer

In a simple protein molecule in aqueous solution, the charged groups are almost all on the surface. This is because the aqueous environment tends to solvate the charged groups, which leads to their localization on the surface of the protein where they can interact with water molecules. This also allows the hydrophobic residues to be buried inside the protein where they can interact with each other.

In a Simple Protein Molecule in Aqueous Solution, the Charged