The following question(s) refer to this table of codons.
-A peptide has the sequence NH2-phe-pro-lys-gly-phe-pro-COOH. Which of the following sequences in the coding strand of the DNA could code for this peptide?
A) 3' UUU-CCC-AAA-GGG-UUU-CCC
B) 3' AUG-AAA-GGG-TTT-CCC-AAA-GGG
C) 5' TTT-CCC-AAA-GGG-TTT-CCC
D) 5' GGG-AAA-TTT-AAA-CCC-ACT-GGG
E) 5' ACT-TAC-CAT-AAA-CAT-TAC-UGA

Question

The following question(s) refer to this table of codons. 
-A peptide has the sequence NH2-phe-pro-lys-gly-phe-pro-COOH. Which of the following sequences in the coding strand of the DNA could code for this peptide?
A) 3' UUU-CCC-AAA-GGG-UUU-CCC 
B) 3' AUG-AAA-GGG-TTT-CCC-AAA-GGG 
C) 5' TTT-CCC-AAA-GGG-TTT-CCC 
D) 5' GGG-AAA-TTT-AAA-CCC-ACT-GGG 
E) 5' ACT-TAC-CAT-AAA-CAT-TAC-UGA

Quizplus · Accepted Answer

The correct DNA sequence must match the RNA sequence that codes for the peptide, considering the RNA uses uracil (U) instead of thymine (T). The peptide sequence is NH2-phe-pro-lys-gly-phe-pro-COOH, which translates to the RNA codons Phe (UUU), Pro (CCC), Lys (AAA), Gly (GGG), Phe (UUU), Pro (CCC). The DNA sequence complementary to the RNA codons is 5' TTT-CCC-AAA-GGG-TTT-CCC, which matches option C. DNA is read 5' to 3', and the coding strand is the same sequence as the RNA (with T instead of U).

The Following Question(s) Refer to This Table of Codons