What causes rejection by the body's immune system after a transplant of an improperly matched organ?
I. nonself proteins in the tissue
II. the presence of foreign major histocompatibility complex (MHC) proteins on the donor tissue
III. antibodies and cytotoxic T lymphocytes (CTLs) responding to foreign tissue
A) only I and III
B) only II and III
C) only I and IIII
D) I, II, and III

Question

Quizplus · Accepted Answer

Rejection after an improperly matched organ transplant is caused by multiple factors including non-self proteins in the tissue (I), foreign MHC proteins on the donor tissue (II), and the immune response of antibodies and CTLs to foreign tissue (III). Therefore, all three choices are correct.

What Causes Rejection by the Body's Immune System After a Transplant