Which of the following chemicals can be used to create a reversible lesion in brain tissue?
A) saline
B) a local anesthetic such as lidocaine
C) glutamate
D) flurogold
E) 6-hydroxydopamine

Question

Quizplus · Accepted Answer

A local anesthetic such as lidocaine can be used to create a reversible lesion in brain tissue by blocking sodium channels and preventing action potential generation in neurons. Saline is not a chemical that can create a lesion. Glutamate is an excitatory neurotransmitter and can actually cause damage to brain tissue if levels are too high. Fluorogold is a tracer used to label neurons and 6-hydroxydopamine is a neurotoxin used to specifically destroy dopaminergic neurons in certain experimental models.

Which of the Following Chemicals Can Be Used to Create