The net overall effect of the indirect pathway between the basal ganglia and the motor cortex through ________ is ________ for motor movement.
A) GPi; excitatory
B) GPi; inhibitory
C) GPe; excitatory
D) the hypothalamus; excitatory
E) the substantia nigra; inhibitory

Question

Quizplus · Accepted Answer

The indirect pathway involves the basal ganglia output nucleus GPi, which sends an inhibitory signal to the thalamus, which then sends an inhibitory signal to the motor cortex. This ultimately results in a decrease in motor movement. Therefore, the net overall effect of the indirect pathway is inhibitory for motor movement.

The Net Overall Effect of the Indirect Pathway Between the Basal