Which sequence of hormone treatment is most likely to restore sexual receptivity in an ovariectomized female rat?
A) a small dose of estradiol alone
B) a small dose of oxytocin alone
C) an oxytocin dose followed thereafter by a progesterone dose
D) a small dose of progesterone alone
E) a small dose of estradiol followed by a progesterone dose

Question

Quizplus · Accepted Answer

The most effective sequence of hormone treatment to restore sexual receptivity in ovariectomized female rats is a small dose of estradiol followed by a progesterone dose. Estradiol first primes the brain for the effects of progesterone, which then induces sexual receptivity. Oxytocin alone may facilitate aspects of sexual behavior, but it is not as effective as estradiol and progesterone. A small dose of progesterone alone may have some effect, but it will not be as effective without prior exposure to estradiol.

Which Sequence of Hormone Treatment Is Most Likely to Restore