What technique is most commonly used with nonhumans to determine whether or not a drug has dependence liability?
A)determine if the drug disrupts instrumental behavior
B)determine if they will self-administer the drug
C)determine if the drug has a low therapeutic index
D)determine if tolerance occurs to the drug with repeated exposures

Question

Quizplus · Accepted Answer

The most commonly used technique with nonhumans to determine whether or not a drug has dependence liability is to test if they will self-administer the drug. This is because animals will only self-administer drugs that produce some form of reward or positive experience, which is a strong indication of dependence liability.

What Technique Is Most Commonly Used with Nonhumans to Determine