A DNA sequence has been cut into the following three overlapping sequence fragments:
(1) CCGCGCGTAGCGAGTCAG
(2) GGCTAGTTAGCTCCGCGCG
(3) AGTCAGTCAAAAT
What is the correct assembled sequence of these fragments?
A) GGCTAGTTAGCTCCGCGCGTAGCGAGTCAGTCAAAAT
B) CCGCGCGTAGCGTTAGCTCCGCGCGCAAAGTCAAAAT
C) CCGCGCGTAGCGAGTCAGGGCTAGTTAGCTCCGCGCG
D) AGTCAGTCAAAATGTCAGCAGTCAAAAT
E) GGCTAGTTAGCTCCGCGCGAGTCAGTCAAAAT

Question

A DNA sequence has been cut into the following three overlapping sequence fragments: 
(1) CCGCGCGTAGCGAGTCAG
(2) GGCTAGTTAGCTCCGCGCG
(3) AGTCAGTCAAAAT
What is the correct assembled sequence of these fragments?
A) GGCTAGTTAGCTCCGCGCGTAGCGAGTCAGTCAAAAT
B) CCGCGCGTAGCGTTAGCTCCGCGCGCAAAGTCAAAAT
C) CCGCGCGTAGCGAGTCAGGGCTAGTTAGCTCCGCGCG
D) AGTCAGTCAAAATGTCAGCAGTCAAAAT
E) GGCTAGTTAGCTCCGCGCGAGTCAGTCAAAAT

Quizplus · Accepted Answer

- Fragment 1 ends with "TAGCGAGTCAG"
- Fragment 2 starts with "GGCTAGTTAG"
- Therefore, the two fragments can be overlapped as "TAGCGAGTCAGGGCTAGTTAG"
- Fragment 3 starts with "AGTCAGTCAAAAT" which can be appended to the above overlap
- Thus, the final assembled sequence is "GGCTAGTTAGCTCCGCGCGTAGCGAGTCAGTCAAAAT"

A DNA Sequence Has Been Cut into the Following Three