Which disease would be most difficult to detect with standard pedigree analysis?
A) A multifactorial disease
B) A disease caused by a recessive loss-of-function point mutation
C) A disease caused by a missense mutation
D) A disease caused by a dominant gain-of-function point mutation
E) A disease caused by a base deletion

Question

Quizplus · Accepted Answer

A multifactorial disease is caused by a complex interplay between many different genetic and environmental factors, making it difficult to trace through a standard pedigree analysis. In contrast, diseases caused by a recessive or dominant point mutation or base deletion can often be traced through generations of a family tree.

Which Disease Would Be Most Difficult to Detect with Standard