Fragile-X syndrome
A) is an example of aneuploidy.
B) always results in mental retardation.
C) only affects males.
D) involves repeats of a codon.
E) is an example of a translocation.

Question

Quizplus · Accepted Answer

Fragile-X syndrome involves an expansion of the CGG repeat in the FMR1 gene, which codes for a protein important for synaptic plasticity. This causes the protein to not be produced properly, leading to varying degrees of intellectual disability, anxiety, social and emotional difficulties, and physical characteristics such as a long face and large ears. It is not always present in males or caused by a translocation, and it is not an example of aneuploidy as it does not involve a change in chromosome number.

Fragile-X Syndrome