If a mutation occurs such that splicing does not remove one of the introns in a gene, what effect will this have on the protein encoded by that gene?
A) It will have no effect; the gene will be transcribed and translated into protein.
B) Transcription will terminate early, and the protein will not be made.
C) Transcription will continue, but translation will stop at the site where the intron remains.
D) Translation will continue, but it is likely that a nonfunctional or aberrant protein will be made.
E) Translation will and will skip the intron sequence.

Question

Quizplus · Accepted Answer

If splicing does not remove one of the introns in a gene, the resulting mRNA will contain an additional sequence that should have been removed. This could cause a frameshift mutation, altering the reading frame of the mRNA and resulting in a non-functional or aberrant protein. Alternatively, if the intron sequence is not in-frame, it could result in premature translation termination, leading to a truncated and likely non-functional protein. In some cases, alternative splicing events may be able to circumvent the effects of the intron, but this would depend on the specific context and location of the intron.

If a Mutation Occurs Such That Splicing Does Not Remove