Which is the step in glucagon signaling where adipose triglyceride lipase mediates a reaction?
1)A hydrolysis reaction cleaves a fatty acid from the stored triacylglycerols to generate diacylglycerol and a fatty acid.
2)Perilipin is phosphorylated on the surface of lipid droplets.
3)Albumin transports the free fatty acid.
4)A GDP-GTP exchange stimulates cyclic AMP production by the enzyme adenylate cyclase.
A)1
B)2
C)3
D)4

Question

Quizplus · Accepted Answer

Adipose triglyceride lipase mediates the hydrolysis reaction that cleaves a fatty acid from the stored triacylglycerols to generate diacylglycerol and a fatty acid. Choice B is incorrect because perilipin phosphorylation is a step that regulates access of lipases to the lipid droplet surface, but it is not the step where adipose triglyceride lipase mediates a reaction. Choice C is incorrect because albumin transports the free fatty acid after it is released from the triacylglycerol, but it is not the step where adipose triglyceride lipase is involved. Choice D is incorrect because adenylate cyclase is a downstream effector of glucagon signaling that is stimulated by a GDP-GTP exchange on the G protein alpha subunit, but it is not the step where adipose triglyceride lipase mediates a reaction.

Which Is the Step in Glucagon Signaling Where Adipose Triglyceride