According to the ,which of the following exergonic reactions is most likely irreversible under normal cellular conditions and is considered to be the rate-limiting step of the citrate cycle?
A) citrate synthase
B) fumarase
C) isocitrate dehydrogenase
D) -ketoglutarate dehydrogenase

Question

According to the  ,which of the following exergonic reactions is most likely irreversible under normal cellular conditions and is considered to be the rate-limiting step of the citrate cycle?
A) citrate synthase 
B) fumarase 
C) isocitrate dehydrogenase 
D) -ketoglutarate dehydrogenase

Quizplus · Accepted Answer

The isocitrate dehydrogenase reaction is the most likely irreversible reaction under normal cellular conditions and is considered to be the rate-limiting step of the citrate cycle. The other reactions mentioned are reversible and not typically rate-limiting in the cycle.

According to the ,Which of the Following Exergonic Reactions