Which of the following is true of a recessive oncogene mutation but NOT a dominant oncogene mutation?
A) It results in a disease phenotype any time the mutation is present in a cell.
B) It results in a disease phenotype only when both copies of the mutated oncogene are present in the same cell.
C) It is a gain-of-function mutation.
D) It is a mutation in a tumor suppressor gene.

Question

Quizplus · Accepted Answer

A recessive oncogene mutation will result in a disease phenotype only when both copies of the mutated oncogene are present in the same cell. In contrast, a dominant oncogene mutation will result in a disease phenotype any time the mutation is present in a cell. Both recessive and dominant oncogene mutations are gain-of-function mutations, and neither is a mutation in a tumor suppressor gene.

Which of the Following Is True of a Recessive Oncogene