The Bohr effect refers to the unloading of ________ in a RBC due to declining blood pH.
A) chloride ions
B) carbon dioxide
C) BPG
D) oxygen

Question

Quizplus · Accepted Answer

The Bohr effect specifically refers to the phenomenon in which declining blood pH causes hemoglobin to release oxygen (O2) more readily. As carbon dioxide (CO2) is carried in the blood, it reacts with water to form carbonic acid, which can lead to a decrease in blood pH. Therefore, it indirectly affects the unloading of oxygen, but is not directly responsible for it. Chloride ions (Cl-) and 2,3-bisphosphoglycerate (BPG) are also involved in regulating oxygen binding in the blood, but not specifically in the Bohr effect.

The Bohr Effect Refers to the Unloading of ________ in a RBC