What type of mutation causes conditions such as Huntington's disease and Fragile X syndrome?
A)an excess of trinucleotide repeats in a protein-coding gene
B)a mutation in the p53 tumor suppressor
C)a mutation in a cyclin-dependent protein kinase
D)a mutation in the retinoblastoma gene
E)a mutation in caspase-activated DNase

Question

Quizplus · Accepted Answer

Both Huntington's disease and Fragile X syndrome are caused by an excess of trinucleotide repeats, specifically CAG repeats in the case of Huntington's and CGG repeats in the case of Fragile X. This leads to abnormal protein function and ultimately results in the symptoms of these conditions.

What Type of Mutation Causes Conditions Such as Huntington's Disease