Which of the following is the key regulator of the rate of glycolysis?
A)ATP
B)NADH
C)Phosphofructokinase
D)Glyceraldehyde-3-phosphate
E)FAD

Question

Quizplus · Accepted Answer

Phosphofructokinase is the key regulatory enzyme of the glycolytic pathway, which catalyzes the committed step of glycolysis, the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate. It is allosterically inhibited by ATP, citrate, and H+ ions but activated by ADP, AMP, and fructose 2,6-bisphosphate. Hence, the rate of glycolysis is mainly controlled by the concentration of ADP/ATP and fructose 2,6-bisphosphate in the cell, which regulates the activity of phosphofructokinase.

Which of the Following Is the Key Regulator of the Rate